Publications by authors named "B Cuer"
Objectives: Although oral pre-exposure prophylaxis (PrEP) for HIV is being rolled out in West Africa, data on sexually transmitted infections (STIs) in PrEP users are scarce. We assessed the prevalence, incidence and determinants of bacterial STIs in men who have sex with men (MSM) taking PrEP in Burkina Faso, Côte d'Ivoire, Mali and Togo.
Methods: A prospective cohort study among MSM initiating PrEP as part of a comprehensive HIV prevention package was conducted between 2017 and 2021 in community-based clinics in the four study countries.
Introduction: People living with HIV are considered at higher risk of developing severe forms of tuberculosis (TB) disease. Providing HIV testing to TB-exposed people is therefore critical. We present the results of integrating HIV testing into a community-based intervention for household TB contact management in Cameroon and Uganda.
View Article and Find Full Text PDFBackground: Globally, the uptake of tuberculosis-preventive treatment (TPT) among children with household tuberculosis contact remains low, partly due to the necessity of bringing children to health facilities for investigations. This study aimed to evaluate the effect on TPT initiation and completion of community-based approaches to tuberculosis contact investigations in Cameroon and Uganda.
Methods: We did a parallel, cluster-randomised, controlled trial across 20 clusters (consisting of 25 district hospitals and primary health centres) in Cameroon and Uganda, which were randomised (1:1) to receive a community-based approach (intervention group) or standard-of-care facility-based approach to contact screening and management (control group).
Article Synopsis
- A study in West Africa from 2017-2021 observed HIV seroconversion among men who have sex with men (MSM) using either event-driven or daily pre-exposure prophylaxis (PrEP) in Burkina Faso, Côte d'Ivoire, Mali, and Togo.
- 647 high-risk HIV-seronegative MSM participated, with 72.1% opting for event-driven PrEP, which had a higher HIV incidence (2.4 per 100 person-years) compared to daily PrEP (0.6 per 100 person-years).
- The study found lower adherence rates for event-driven PrEP (44.3%) compared to daily PrEP (74.9%), indicating a critical need for
Article Synopsis
- Patient-reported outcomes like health-related quality of life (HRQoL) are crucial in cancer trials, but dropout rates among participants can lead to missing data and biased results.
- The study compares the standard linear mixed model to a joint model that accounts for both HRQoL and dropout to identify when biases occur due to differences in patient outcomes.
- Findings indicate that using the linear mixed model can incorrectly estimate HRQoL and skew comparisons between treatment groups, especially when poorer HRQoL correlates with higher dropout risks.