Publications by authors named "B Contino"

The objective of this work is to assess the 5-year outcomes of patients undergoing conization for high-grade cervical lesions that simultaneously present as risk factors in the persistence of HPV infection and the positivity of surgical resection margins. This is a retrospective study evaluating patients undergoing conization for high-grade cervical lesions. All patients included had both positive surgical margins and experienced HPV persistence at 6 months.

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Cervical dysplasia persistence/recurrence has a great impact on women's health and quality of life. In this study, we investigated whether a prognostic nomogram may improve risk assessment after primary conization. This is a retrospective multi-institutional study based on charts of consecutive patients undergoing conization between 1 January 2010 and 31 December 2014.

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Article Synopsis
  • The study aimed to assess the outcomes of high-risk HPV-positive and negative women with high-grade cervical dysplasia through a retrospective analysis of medical records from 2010 to 2014.
  • A total of 2,966 women were included, with 85% being HR-HPV-positive; results indicated that HR-HPV-positive patients had a significantly higher risk of recurrence after conization compared to HR-HPV-negative patients.
  • The findings suggest that while HR-HPV-negative high-grade dysplasia accounts for 15% of cases, these patients generally have better outcomes, highlighting the need for further research to validate these results.
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: Primary prevention through vaccination is a prophylactic approach aiming to reduce the risk of developing human papillomavirus (HPV)-related lesions. No mature and long-term data supported the adoption of vaccination in women undergoing conization. This is a retrospective multi-institutional study.

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Objective: Conization aims to remove pre-neoplastic lesions of the uterine cervix. Several techniques for conization have been compared, but evidence regarding the most effective therapeutic option is scant. Here, we aimed to compare the recurrence rate following laser conization and loop electrosurgical excision procedure (LEEP) in patients with high-grade cervical dysplasia (HSIL/CIN2+).

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