Publications by authors named "B Connolly"
Background: Animal-assisted interventions (AAI) can provide psychological support to critical care patients during their intensive care unit (ICU) admission. However, there are currently no data on AAI services across UK ICUs. The current study therefore aims to (i) determine how many ICUs in the UK offer services, (ii) characterise available services and (iii) explore and review local documentation for service oversight.
View Article and Find Full Text PDFArticle Synopsis
- - SLPI is a key protein that plays a role in airway immunity by inhibiting harmful enzymatic activity, and it also has anti-inflammatory effects by regulating immune responses through NF-κB inhibition.
- - In lung diseases like COPD and Cystic Fibrosis, SLPI levels can be elevated due to inflammation, but some studies show that COPD patients may have lower SLPI levels, which could weaken airway immunity.
- - Researchers are using a mouse model that mimics features of COPD and CF to study the effects of SLPI by creating a genetically modified mouse (ENaC-Tg/SLPI) to understand how the absence of SLPI influences the progression of these chronic lung diseases.
Background: Neuroangiography represents a critical diagnostic and therapeutic imaging modality whose associated radiation may be of concern in children. The availability of in vivo radiation damage markers would represent a key advancement for understanding radiation effects and aid in the development of radioprotective strategies.
Objective: Determine if biomarkers of cellular damage can be detected in the peripheral blood mononuclear cells (PBMC) of children undergoing neuroangiography.