Publications by authors named "B Conio"

: mechanical restraint (MR) is a controversial issue in emergency psychiatry and should be better studied to implement other alternative therapeutic interventions. The aim of this study was to estimate the prevalence of MR in an Italian psychiatric unit and identify the sociodemographic and clinical characteristics as well as the pharmacological pattern associated with MR. : all subjects (N = 799) consecutively admitted to an Italian psychiatric inpatient unit were recruited.

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Objective: While pharmacological strategies appear to be ineffective in treating long-term addiction, repetitive transcranial magnetic stimulation (rTMS) is emerging as a promising new tool for the attenuation of craving among multiple substance dependent populations.

Method: A systematic review of randomized controlled trials (RCTs) was conducted on the efficacy and tolerability of rTMS in treating cocaine use disorder (CUD). Relevant papers published in English through November 30 2022 were identified, searching the electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Library.

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Article Synopsis
  • This study examines the link between chronotype (individual sleep patterns) and cardiometabolic health in patients with bipolar disorder (BD).
  • Researchers analyzed data from 170 BD patients, assessing their chronotype and performing blood tests to evaluate cholesterol and body mass index (BMI).
  • Findings indicate that patients with an evening chronotype had higher BMI and cholesterol levels, suggesting a potential connection between sleep patterns and increased obesity and cardiovascular risk in those with BD.
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Article Synopsis
  • Schizophrenia is a complicated mental health disorder that might be linked to problems with the immune system.
  • The review highlights new evidence connecting immune dysfunction to schizophrenia's clinical features, expanding on previous genetic and molecular research.
  • It proposes a hypothesis about how immune cells, especially microglia, play a role in the development of schizophrenia, aiming to improve understanding and treatment of the disorder.
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Sirtuin 1 (SIRT1) is a sensor of cell energy availability, regulating metabolic homeostasis as well as leptin and ghrelin, and it could be considered as a potential plasmatic marker. The aim of this study was to assess whether circulating SIRT1 varies consistently with leptin, ghrelin, body mass index (BMI), and IgG reactive to hypothalamic antigens in anorexia nervosa (AN). Fifty-four subjects were evaluated: 32 with AN and 22 normal-weight control subjects.

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