Publications by authors named "B Coleiro"
Objectives: The study aim was to evaluate the estimated glomerular filtration rate (eGFR), its association with clinical disease and its predictive ability with respect to mortality in SSc patients from the European Scleroderma Trials and Research Group (EUSTAR) database.
Methods: SSc patients from the EUSTAR database who had items required for the calculation of eGFR at a baseline visit and a second follow-up visit available were included. A cut-off eGFR value of 60 ml/min was chosen for all SSc patients, and 30 ml/min for those with scleroderma renal crisis (SRC).
Article Synopsis
- A 31-year-old woman was hospitalized with a 7-week fever of unknown origin, experiencing additional symptoms like night sweats.
- Despite extensive testing, her condition remained undiagnosed until she developed a rash and hearing loss.
- A diagnosis of Cogan's syndrome was made after it was confirmed as vasculitis, and her symptoms improved significantly with immunosuppressive therapy, highlighting the importance of early diagnosis for effective treatment.
Congenital tufting enteropathy is a rare condition which presents in early infancy. It is a condition which should be suspected in infants who present with diarrhoea soon after birth. A rare association with arthritis has been observed with a handful of cases documented in the literature.
View Article and Find Full Text PDFBackground. TNF-α inhibitors have shown to be effective in reducing disease activity and improving the quality of life. Due to the high costs associated with acquisition of this treatment, this study was undertaken to evaluate the ICER of TNF-α antagonists (etanercept, adalimumab, and infliximab) in improving the quality of life.
View Article and Find Full Text PDFObjectives: To determine the causes and predictors of mortality in systemic sclerosis (SSc).
Methods: Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities.