Publications by authors named "B Citgez"
Breast Cancer Recurrence in Initially Clinically Node-Positive Patients Undergoing Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in the NEOSENTITURK-Trials MF18-02/18-03.
Ann Surg Oncol
December 2024
Background: This study aims to identify factors predicting recurrence and unfavorable prognosis in cN+ patients who have undergone sentinel lymph node biopsy (SLNB) following neoadjuvant chemotherapy (NAC).
Methods: The retrospective multi-centre "MF18-02" and the prospective multi-centre cohort registry trial "MF18-03" (NCT04250129) included patients with cT1-4N1-3M0 with SLNB+/- axillary lymph node dissection (ALND) post-NAC.
Results: A total of 2407 cN+ patients, who later achieved cN0 status after NAC and subsequently underwent SLNB, were studied.
Article Synopsis
- The study investigates the safety of omitting axillary lymph node dissection (ALND) in patients with residual axillary disease after neoadjuvant chemotherapy (NAC), focusing on those treated with sentinel lymph node biopsy (SLNB) or targeted axillary dissection (TAD).
- An analysis of two multicenter cohorts (MF18-02 and MF18-03) included 501 patients who received regional nodal irradiation and achieved a complete clinical response to NAC.
- Results showed low recurrence rates (0.4% axillary, 0.8% locoregional) and no significant differences in disease-free or disease-specific survival between SLNB and TAD, suggesting ALND omission is safe if patients receive
Article Synopsis
- The study investigates how glutamine and omega-3 fatty acids influence the growth of intestinal neomucosa in a model for short bowel syndrome using male rats.
- 32 rats were divided into four groups: sham, control, glutamine, and omega-3, and underwent surgeries to assess the healing process over 14 days with measured outcomes.
- Results showed that glutamine significantly improved the formation of intestinal neomucosa in 100% of rats, while omega-3 and control groups showed lower success, indicating glutamine's stronger impact on healing and inflammation response.
Identification of Risk Factors for Mastalgia and Its Relationship with Benign or Malignant Breast Diseases.
Sisli Etfal Hastan Tip Bul
December 2023
Objectives: Mastalgia is a medical condition that primarily affects women of all age groups. Affected individuals experience excruciating pain, tightness, or a burning sensation in the breast tissue. The aim of this study is to observe the clinicopathologic features of women with mastalgia and compare these features with asymptomatic cases.
View Article and Find Full Text PDFBackground: Antioxidants have been considered a rational curative strategy to prevent and cure liver diseases involving oxidative stress. An acute obstructive jaundice rat model was established to investigate the in vivo hepatoprotective efficacy of Rosa pimpinellifolia L.
Methods: The experimental jaundice model was performed by binding the main bile duct in 25 male Sprague-Dawley rats.