Publications by authors named "B Christine Penney"

Article Synopsis
  • This study evaluated how well high-definition (HD) PET imaging measures and predicts outcomes in non-small cell lung cancer (NSCLC) patients, compared to standard-definition (SD) PET imaging.
  • The study included 242 NSCLC patients, revealing that HD PET produced higher standardized uptake values (SUV) and tumor-to-background ratios (TBR) than SD PET.
  • Interestingly, while both imaging techniques showed a connection between SUV and overall survival, only the SUV from SD PET remained significantly linked to survival after adjusting for clinical stage.
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Background: Alabama is one of seven priority states for the National Ending the HIV Epidemic Initiative due to a disproportionate burden of rural infections. To reverse growing infection rates, the state must increase its focus on prevention efforts, including novel strategies. One such approach is to utilize dashboards that visualize real-time data on the pre-exposure prophylaxis (PrEP) care continuum to assist in prioritizing evidence-based preventative care for those most vulnerable for HIV infection.

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There is limited understanding of how mechanical signals regulate tendon development. The nucleus has emerged as a major regulator of cellular mechanosensation, via the linker of nucleoskeleton and cytoskeleton (LINC) protein complex. Specific roles of LINC in tenogenesis have not been explored.

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Background: Using the Asset Bundle Model, we sought to understand the social support assets and needs of underrepresented minority (URM) high school, undergraduate, and graduate students.

Setting: Study participants were or had participated in health sciences pathway programs at Birmingham City Schools and/or the University of Alabama at Birmingham.

Methods: We took a concurrent mixed methods approach to conduct an environmental scan of health science pathway programs in the Birmingham, AL area.

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The extracellular microenvironment regulates many of the mechanical and biochemical cues that direct musculoskeletal development and are involved in musculoskeletal disease. The extracellular matrix (ECM) is a main component of this microenvironment. Tissue engineered approaches towards regenerating muscle, cartilage, tendon, and bone target the ECM because it supplies critical signals for regenerating musculoskeletal tissues.

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