Publications by authors named "B Chindo"

Article Synopsis
  • Researchers studied how a plant called Ficus platyphylla (FP) can help rats that have seizures and brain problems caused by a chemical called PTZ.
  • They found that giving the rats FP improved their seizures, brain health, and mood when compared to rats that did not receive the plant extract.
  • The study suggests that FP might be useful in treating epilepsy and related mental health issues by reducing harmful stress in the brain.
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Article Synopsis
  • * The study investigated the anticancer effects of the chloroform root extract from the herb Burm on liver cancer induced in mice using specific chemicals.
  • * Results showed that the extract reduced liver enzyme toxicity, promoted apoptotic cell death in cancer cells, and significantly increased the expression of apoptotic genes, suggesting it may effectively induce apoptosis in liver cancer.
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Ethnopharmacological Relevance: Caralluma dalzielii (Asclepiadiaceae) is a shrub used in folkloric medicine to treat epilepsy, pain and infertility in sub-Saharan Africa. Previous studies demonstrated its analgesic, antiulcer, anticonvulsant, and anti-inflammatory activities.

Aim: This study aimed to determine the neurobehavioural properties of Caralluma dalzielii aqueous aerial parts extract (CDAE) in mice using standard experimental models.

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Ethnopharmacological Relevance: Melissa officinalis L. (Lamiaceae) is a medicinal plant native to Mediterranean regions and found in other parts of the world. Extracts and essential oil from this widely cultivated culinary medicinal herb are used in traditional medicine to manage a variety of disorders that include epilepsy and pain.

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L. is used in traditional European and Iranian folk medicines to treat a plethora of neurological diseases including epilepsy. We utilized the and models of epilepsy to probe the anticonvulsant potentials of essential oil from (MO) to gain insight into the scientific basis for its applications in traditional medicine for the management of convulsive disorders.

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