Publications by authors named "B Charron"
Article Synopsis
- The study focuses on identifying risk factors for early postoperative complications and mortality in patients undergoing surgeries for metastatic bone disease, highlighting the growing importance of assessing surgical outcomes as cancer survivorship improves.
- Researchers conducted a retrospective review of 185 patients who had either prophylactic fixation or stabilization of pathologic fractures between 2005 and 2020, excluding certain surgeries and conditions for a clearer analysis.
- The findings revealed a 30-day complication rate of 32.30% and a mortality rate of 17.26%, identifying factors such as pathologic fractures, extra-skeletal metastases, and specific cancer types (like lung cancer) as significant predictors of complications and mortality post-surgery.
Background: The incidence of total joint arthroplasty is increasing, with added emphasis on shifting care toward outpatient surgery. This has demonstrated improvements in costs and care; however, safety must be prioritized. Published assessment tools highlight candidates for outpatient surgery; however, they often do not define patients who have a worse prognosis.
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- Bovine serum albumin (BSA) is commonly used in biosensing as a blocking buffer, but human serum albumin (HSA) has a significant impact on binding assays and has been underexplored.
- A study utilized surface plasmon resonance (SPR) to investigate the effects of different albumins and human serum on a simple binding assay involving human IgG and goat anti-human IgG, revealing that HSA substantially influences the SPR shifts and binding constants.
- The findings suggest BSA is effective for surface blocking but recommend using HSA for optimizing assays intended for clinical applications involving human blood or serum, highlighting the necessity of considering specific protein interactions in such contexts.
This paper describes a robust dynamic spectroscopic ellipsometer that can provide a highly accurate and reliable real-time spectroscopic polarization measurement capability for various in-line nanoscale measurement applications. The robustness of dynamic spectroscopic ellipsometry is enhanced significantly by employing a compensation channel that removes the temperature dependency of the monolithic polarizing interferometric module, and it results in highly accurate dynamic spectral ellipsometric measurements. We present how the monolithic interferometer is affected by external disturbances and show experimentally that the proposed scheme can provide a few hundreds of times long-term stability enhancement compared with a single-channel-based dynamic spectroscopic ellipsometer scheme.
View Article and Find Full Text PDFA series of thermally shrinkable polymer surface-enhanced Raman scattering (SERS) substrates were prepared with bimetallic Au and Ag (oxidized or not) films and with Au nanoparticles (AuNPs) located at different places in the layered structure to evaluate the synergistic effect of different known SERS amplification methods to enhance the Raman signal for low concentration dopamine detection. A bimetallic Au and Ag layered structure improved the Raman signal by 5 and 2 times compared to the single-layered Au and Ag films. Oxidizing the Ag layer prior to deposition of Au further improved the signal by a factor of 2, while adding AuNP on wrinkled films increased another 10 times the intensity of the Raman signal.
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