Physiological correlates of a simple saccadic-decision task to extended objects in superior colliculus.

Our vision is best only in the center of our gaze, and we use saccadic eye movements to direct gaze to objects and features of interest. We make more than 180,000 saccades per day, and accurate and efficient saccades are crucial for most visuo-motor tasks. Saccades are typically studied using small point stimuli, despite the fact that most real-world visual scenes are composed of extended objects.

Perceptual confidence judgments reflect self-consistency.

Each perceptual decision is commonly attached to a judgment of confidence in the uncertainty of that decision. Confidence is classically defined as the estimate of the posterior probability of the decision to be correct, given the evidence. Here we argue that correctness is neither a valid normative statement of what observers should be doing after their perceptual decision nor a proper descriptive statement of what they actually do.

Spatial modulation of hippocampal activity in freely moving macaques.

The hippocampal formation is linked to spatial navigation, but there is little corroboration from freely moving primates with concurrent monitoring of head and gaze stances. We recorded neural activity across hippocampal regions in rhesus macaques during free foraging in an open environment while tracking their head and eye. Theta activity was intermittently present at movement onset and modulated by saccades.

Supporting generalization in non-human primate behavior by tapping into structural knowledge: Examples from sensorimotor mappings, inference, and decision-making.

The complex behaviors we ultimately wish to understand are far from those currently used in systems neuroscience laboratories. A salient difference are the closed loops between action and perception prominently present in natural but not laboratory behaviors. The framework of reinforcement learning and control naturally wades across action and perception, and thus is poised to inform the neurosciences of tomorrow, not only from a data analyses and modeling framework, but also in guiding experimental design.