Publications by authors named "B Castan"

SHORTENED ANTIMICROBIAL THERAPY DURATION. Antibiotic treatment durations represent an important field of current clinical research. Indeed, shortening antibiotic duration during bacterial pathologies has several advantages: reducing the emergence of resistance on an individual and collective scale, reducing costs, adverse effects and the environmental impact.

View Article and Find Full Text PDF

Background: This study describes the conditions of use of ceftolozane/tazobactam (C/T) and associated outcomes in French hospital settings.

Methods: This was a prospective, multicenter, French observational study. Patients who received at least 1 dose of C/T were included and followed up as per routine clinical practice, until stop of C/T.

View Article and Find Full Text PDF
Article Synopsis
  • In March 2020, the International Working Group on the Diabetic Foot published updated guidelines on diabetic foot infections, which were endorsed by the French ID society, SPILF, prompting them to revise their own 2006 guidelines.
  • The new recommendations focus on microbiological diagnosis, antibiotic treatment options, and emphasize a multidisciplinary approach for managing diabetic foot infections.
  • Key points include the necessity of staging the infection severity, proper sampling protocols, tailored empirical antibiotic therapy based on infection grade, and the importance of reevaluating treatment duration, especially when osteomyelitis is suspected.
View Article and Find Full Text PDF