Publications by authors named "B Casis"
Background And Aims: Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied.
Methods: This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Background: The usefulness of thiopurines has been poorly explored in pouchitis and other pouch disorders.
Objective: To evaluate the effectiveness and safety of azathioprine as maintenance therapy in inflammatory pouch disorders.
Design: This was a retrospective and multicentre study.
Background: Optimal golimumab concentration thresholds for important outcomes during maintenance are lacking.
Aims: To investigate the association of golimumab trough concentrations during maintenance with key outcomes, including endoscopic and histologic remission, and long-term event-free persistence with golimumab, in patients with UC.
Methods: This multi-centre, cross-sectional study included patients with UC on golimumab maintenance recruited either in remission or during a flare.
Preferences and satisfaction of IBD patients after switching from adalimumab 40 mg weekly to 80 mg every other week given as a single injection: the ADASCAL study.
Therap Adv Gastroenterol
November 2021
Article Synopsis
- * Results indicated high levels of satisfaction with the 80 mg EOW regimen, reflected in a total TSQM score of 83.4, and most patients (74%) preferred the new regimen for its effectiveness and convenience, with minimal interference in daily activities.
- * Health-related quality of life scores were also high, with participants reporting an average EQ-5D score of 72.3 and SIBDQ-9 score of 75.1, suggesting the new dosing regimen positively impacted the
In recent years, the incidence of inflammatory bowel disease (IBD) has been on the rise, extending to countries where it was infrequent in the past. As a result, the gap between high and low incidence countries is decreasing. The disease, therefore, has an important economic impact on the healthcare system.
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