(1) Background: Metastatic L-type sarcomas (liposarcoma and leiomyosarcoma) are rare and have a poor prognosis. Trabectedin is an effective agent that can be used after anthracyclines. This study was designed to evaluate the real-life effectiveness and safety of trabectedin.
View Article and Find Full Text PDFThis study aimed to reveal the morphological characteristics of pure Holstein and Simmental skulls and to obtain reference values for morphometric analysis. Moreover, 54 skulls from 12- to 14-month-old male Holstein ( = 25) and Simmental ( = 29) cattle were collected from Turkey's Southeastern Anatolia Region between 2023 and 2024. Linear measurements indicated that Holsteins had longer skulls compared to Simmentals.
View Article and Find Full Text PDFSelective breeding over centuries has led to the emergence of numerous pigeon breeds from the single species Columba livia, showcasing unparalleled phenotypic diversity. In Eastern Turkey, Van pigeons originate, while Tumbler pigeon varieties thrive countrywide, reflecting local traditions. The avian beak, vital for survival, offers insights into domestication and traits influenced by natural selection.
View Article and Find Full Text PDFIntroduction: Although long-term survival in patients with metastatic colorectal cancer (mCRC) is limited, treatments for third-line and later treatment are now recommended. We describe a patient who achieved long-term survival when they received third-line treatment with trifluridine/tipiracil (FTD/TPI).
Case Presentation: The woman who was 52 years old at diagnosis of adenocarcinoma of the right colon (T3/N0/M1) with metastases to the lung, liver, ovary, and other soft tissues received first-line fluoropyrimidine-based chemotherapy (FOLFOX/FOLFIRI plus bevacizumab) intermittently for approximately 8.