Aesthetic Plast Surg
January 2025
Bromhidrosis significantly impacts individuals' social, professional, and emotional well-being. Traditional treatments such as en bloc excision and alcohol injections are now less favored due to associated complications and suboptimal outcomes. Current evidence identifies botulinum toxin A (BTX-A) as the first-line treatment for mild to moderate cases (Grade 0-2), attributed to its high efficacy, excellent safety profile, and minimally invasive nature.
View Article and Find Full Text PDFContext: Celastrol, acknowledged as a prominent exemplar of the potential for transforming traditional medicinal compounds into contemporary pharmaceuticals, has garnered considerable attention owing to its extensive pharmacological activities. The increasing volume of publications concerning celastrol highlights its importance in current scientific inquiry. Despite the growing interest in this compound, a bibliometric analysis focused on this subject remains to be undertaken.
View Article and Find Full Text PDFBacterial infection and inadequate osseointegration represent significant challenges in the application of titanium (Ti)-based bone implants. Surface modification presents a promising strategy to address these obstacles. Taking advantage of silver ions, black phosphorus nanosheets (BPNs) and polydopamine (PDA), this study developed a versatile platform on the surface of Ti-12Mo-10Zr (TMZ) alloy through a multiple surface modification process, including the anodic oxidation treatment of TMZ alloy, the preparation and addition of silver-loaded BPNs (BPNs/Ag), and the coating with PDA.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
December 2024
Large bone defects are a major clinical challenge in bone reconstructive surgery. 3D printing is a powerful technology that enables the manufacture of custom tissue-engineered scaffolds for bone regeneration. Electrical stimulation (ES) is a treatment method for external bone defects that compensates for damaged internal electrical signals and stimulates cell proliferation and differentiation.
View Article and Find Full Text PDFToxicol Appl Pharmacol
December 2024
The elevated risk of cardiovascular disease (CVD) associated with inflammatory rheumatic diseases has long been recognized. Patients with established rheumatoid arthritis (RA) have a higher mortality rate compared to the general population due to abnormal platelet activation. Thymidine phosphorylase (TYMP) plays a crucial role in platelet activation and thrombosis, following bridging the link between RA and CVD.
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