Publications by authors named "B C Wen"
Background: The DL-3-n-butylphthalide (NBP), a multi-target neuroprotective drug, improving cognitive impairment in patient with vascular cognitive impairment has been confirmed. The efficacy of NBP in patients with cognitive impairment due to Alzheimer's disease (AD) remains unknown. This study aimed to evaluate the efficacy and safety of NBP in patients with mild cognitive impairment (MCI) due to AD though a clinical randomized controlled trail.
View Article and Find Full Text PDFRheumatoid arthritis (RA) is a common chronic autoimmune disease that primarily affects the joints, leading to synovial inflammation and hyperplasia, which subsequently causes joint pain, swelling, and damage. The microenvironment of RA is characterized by hypoxia, high reactive oxygen species (ROS), low pH, and levels of high inflammatory factors. Traditional treatments only partially alleviate symptoms and often cause various adverse reactions with long-term use.
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- The study assesses a novel MRI radiomics stacking ensemble learning model for predicting outcomes of high-intensity focused ultrasound (HIFU) ablation in patients with uterine fibroids.
- Data from 360 patients is analyzed, utilizing deep learning for automated segmentation and various statistical methods for feature selection to enhance predictive accuracy.
- Results showed that among the models tested, the Multilayer Perceptron (MLP) performed the best with an area under the curve (AUC) of 0.858, indicating strong potential for preoperative prognosis using MRI features.
Twenty-one compounds were isolated and identified from the ethanol extract of (Kom.) Nakai, including two new compounds ( and ), a new artificial product () and eighteen known compounds (). Compounds and were isolated from for the first time.
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