Publications by authors named "B C Medeiros"
The genetic diversity of Breton horses in Brazil is a critical concern, mainly due to the small population size and low number of births per year. Given that the inbreeding was overlooked by breeders for multiple generations, we estimated the genetic diversity of this population utilizing pedigree-based measures of population diversity. A total of 1394 six-generation pedigrees representing the full population of registered Breton horses in Brazil defined a total population (TP, = 2679), with horses born between 2000 and 2022, reproductively active and alive, as reported by the breed association, representing the reference population (RP, = 731).
View Article and Find Full Text PDFThe aim of this study was to evaluate the effects of chrysin on the ventral prostate of spontaneously hypertensive rats (SHR). Ten-week-old male Wistar and SHR rats received 100 mg/kg/day of chrysin (TW and TSHR) or 200 µL/day of the dilution vehicle (CW and CSHR) for 70 days. After the treatment, the animals were euthanized and the prostates were dissected out, fixed, and processed for further morphological, immunohistochemical, and biochemical analyses.
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- * An aqueous extract of the plant was prepared and tested in rats, revealing that while there were some symptoms indicative of toxicity, the overall lethality was low, with most animals surviving.
- * The examination of organs post-mortem indicated some necrosis and other changes in dead rats, but overall, the extracted plant showed low toxicity effects on body mass and organ macroscopic evaluation.