Publications by authors named "B C Machen"

In the course of examining 1,000 patients with various neurological complaints, 17 were found to have abnormalities in the region of the pineal gland. Fourteen had no hydrocephalus or symptoms referable to the region of the midbrain but a well-defined region of the high signal on T2 weighted images was demonstrated on magnetic resonance imaging. The other three patients proved to have pineal tumors.

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We studied the normal and abnormal morphology of the corpus callosum in 450 midline sagittal magnetic resonance scans. Clinical information was required to differentiate acquired and congenital defects. Four forms of congenital anomalies were observed: focal attenuations, cysts, partial agenesis, and complete agenesis.

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Two patients with uncontrollable complex partial seizures had normal findings on pre- and postinfusion computed tomography scans. Magnetic resonance imaging demonstrated, in both patients, a lesion in the temporal lobe suggestive of mesial temporal sclerosis. One patient underwent temporal lobectomy, and the radiologic diagnosis was verified.

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Neuronal ceroid lipofuscinosis is a group of neurodegenerative disorders characterized by accumulation of lipofuscin and/or ceroid within the tissues of the body. These entities are manifest by visual, intellectual, and motor deterioration as well as recurrent seizures. Computed tomography has been shown to demonstrate changes of cerebral atrophy in more severely affected patients.

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Intracranial convolutional or gyriform calcification simulating Sturge-Weber syndrome has been described in association with bacterial and viral intracranial infection as well as irradiation and intrathecal methotrexate for central nervous system leukemia. Reported is a case of gyriform calcification caused by chemical meningitis secondary to subarachnoid fat from an epidermoid tumor.

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