Reliability of the Alberta Infant Motor Scale (AIMS) When Used via Telehealth for Neurodevelopmentally High-Risk Infants.

Aims: To assess the reliability of the Alberta Infant Motor Scale (AIMS) when conducted recorded telehealth sessions by novice and expert raters.

Methods: Ten assessors (six novice, four expert) independently rated recorded telehealth assessments of 23 neurodevelopmentally high-risk infants twice. Inter- and intra-rater reliability of subscale scores, total score and percentile rankings were determined.

A new statistical metric for robust target detection in cryo-EM using 2D template matching.

2D template matching (2DTM) can be used to detect molecules and their assemblies in cellular cryo-EM images with high positional and orientational accuracy. While 2DTM successfully detects spherical targets such as large ribosomal subunits, challenges remain in detecting smaller and more aspherical targets in various environments. In this work, a novel 2DTM metric, referred to as the 2DTM p-value, is developed to extend the 2DTM framework to more complex applications.

Indications and Outcomes for Tracheostomies in Pediatric Oncology Patients-A Single Center Study.

Background: Children with cancer face a high risk of complications including prolonged mechanical ventilation requiring tracheostomies. While tracheostomies have been demonstrated to be a generally safe procedure, there remain significant rare complications and a paucity of literature addressing outcomes specifically for pediatric patients with cancer. The objective of this study was to characterize pediatric patients with cancer who underwent tracheostomies and describe their indications and outcomes for length of stay, decannulation, and complications.

A systematic review of lifestyle-based interventions for managing Alzheimer's disease: Insights from randomized controlled trials.

Background: Alzheimer's disease (AD) presents a significant challenge in healthcare, prompting exploration into non-pharmacological interventions to complement traditional treatments.

Objective: This systematic review explores the efficacy of lifestyle-based interventions in managing AD.

Methods: A comprehensive literature search was conducted in PubMed, Web of Science, and Scopus between 2018 and 2023, selecting randomized controlled trials examining factors such as exercise, diet, stress, and cognitive training in AD patients.

A penicillin allergy stewardship team to address unconfirmed pediatric penicillin allergies in Houston, Texas.

Background: Penicillin (PCN) allergy labels are the most common drug allergy label and limit use of first-line antibiotics for many pediatric bacterial infections. Improving access to PCN allergy evaluations is a priority for allergy and immunology (A&I) and infectious diseases (ID) programs.

Objective: To increase the number of completed PCN allergy evaluations from 6 to 24 per month from January 2022 to December 2023.