Cross sectional associations of physical activity and sleep with mental health among Chinese university students.

Objective: This study aimed to examine the levels of physical activity (PA), sleep, and mental health (MH), specifically depression, anxiety, and stress, among Chinese university students. It also aimed to analyze the influencing factors of MH, providing a theoretical foundation for developing intervention programs to improve college students' mental health.

Methods: A stratified, clustered, and phased sampling method was employed.

A Greedy Tabu Dual Heuristic algorithm for the cyclic pickup and delivery problem with 3D loading constraints.

The optimization of auto parts supply chain logistics plays a decisive role in the development of the automotive industry. To reduce logistics costs and improve transportation efficiency, this paper addresses the joint optimization problem of multi-vehicle pickup and delivery transportation paths under time window constraints, coupled with the three-dimensional loading of goods. The model considers mixed time windows, three-dimensional loading constraints, cyclic pickup and delivery paths, varying vehicle loads and volumes, flow balance, and time window constraints.

Characteristics of compression wave propagation and energy absorption effects in dry sandy soil.

The mechanical responses of sandy soil under dynamic loading is closely related to protective engineering and geotechnical engineering, is still not fully understood. To investigate the energy attenuation law and propagation velocity of compressed waves in dry sandy soil, this paper focuses on the dynamic response of compression waves in the specimen under single impact and repetitive impact conditions using an improved split Hopkinson pressure bar (SHPB). The results reveal that the length of the specimen follows an exponential relationship with the attenuation of the peak stress.

Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials.

The immune escape capacities of XBB variants necessitate the authorization of vaccines with these antigens. In this study, we produce three recombinant trimeric proteins from the RBD sequences of Delta, BA.5, and XBB.

Melatonin promotes the proliferation and differentiation of antler chondrocytes via RUNX2 dependent on the interaction between NOTCH1 and SHH signaling pathways.

Melatonin (MT), an endogenous hormone secreted by pineal gland, has the sedative, anti-inflammatory and antioxidant functions. However, there are few studies on whether MT affects the proliferation and differentiation of antler chondrocytes. The present study investigated the influences of MT on the proliferation and differentiation of antler chondrocytes, explored its regulation on runt-related transcription factor 2 (RUNX2), NOTCH1 and sonic hedgehog (SHH) signaling, and elucidated their interplays.