[Evaluation by electrocorticogram of the protective action of piridoxilate against cerebral hypoxia in rats].

Piridoxilate, at the concentration of 120 mg/kg i.p. in rats, enhanced resistance of these animals to hypoxia (N2 : O2 3,2 %).

[The effect of some pharmacological agents and electroshock on the level of cyclic AMP of the total mouse brain].

Amphetamin, pentobarbital, pargyline, parachlorophenylalanine, pentetrasol and maximal electroshock all increased significantly cyclic AMP in mice whole brain conversely reserpine induced a decrease of cyclic nucleotide. All those changes were tentatively correlated toward central monoaminergic systems activation.