Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling.

Myocardial fibrosis (MF), a common event that develops after myocardial infarction, initially is a reparative process but eventually leads to heart failure and sudden cardiac arrest. In MF, the infarct area is replaced by a collagenous-based scar induced by "excessive" collagen deposition from activated cardiac fibroblasts. The scar prevents ventricular wall thinning; however, over time it expands to noninfarcted myocardium.

Cancer of the liver; needle biopsy as a means of detection.

Needle biopsy of the liver was done in 25 patients suspected of having hepatic cancer. The results of biopsy were "positive" in 19 cases, and cancer later was proven to be absent in the livers of four of the other six. Multiple biopsy increased the incidence of positive findings.