Publications by authors named "B Busby"
Article Synopsis
- * The authors introduce "stratifications," or specific BED files, that outline different genomic contexts for GRCh37/38 and the new T2T-CHM13 reference, which includes previously challenging regions to sequence.
- * They also compare the performance of sequencing benchmarks across these references, showing how difficult regions in CHM13 impact the overall performance, and provide a snakemake pipeline for generating stratifications to aid in optimizing sequencing platforms.
Article Synopsis
- The study investigates how clonal hematopoiesis (CH) may lead to myeloid neoplasms (MN) and explores the potential of the plasma proteome in predicting MN risk.
- Researchers analyzed the plasma proteomic profiles of over 46,000 individuals and identified 115 proteins linked to MN risk, with 34 of these also associated with CH.
- The findings suggest that immune system regulation plays a crucial role in the progression from CH to MN, and the use of plasma proteomics can enhance MN risk prediction beyond traditional clinical factors.
Here, we report draft genomic sequences from three isolates, the causative agent of American Foulbrood (AFB), obtained from honeybee colonies of in Fiji, which allow both enterobacterial repetitive intergenic consensus and multilocus sequence typing genotypes to be elucidated for Fijian AFB.
View Article and Find Full Text PDFAn Adaptive, Lightweight, Body-Powered System for Prosthetic Hands Equipped with a Selectively Lockable Differential Mechanism.
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
The need for more practical, robust, and affordable prosthetic hands for amputees has led to significant advancements in their functionality. However, the challenge of designing prostheses that balance dexterity, functionality, and affordability still persists. The lack of prosthetic designs that can efficiently address the needs of amputees for both heavy manual labor and social interactions, while also being lightweight and dexterous, is still evident.
View Article and Find Full Text PDFComplete genomes of isolates from porcine, bovine, and cervine samples found in New Zealand farms.
Microbiol Resour Announc
December 2023
Here, we present complete genome assemblies of strains isolated from porcine, bovine, and cervine farms as part of bacteriology incursion investigations to identify pathogens that might present a sanitary risk to New Zealand.
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