Publications by authors named "B Brunekreef"
Introduction: Exposure to ambient air pollution from combustion-source emissions contributes to the prevalence of asthma, but the role of early-life exposure in asthma development is not well understood. The objective was to examine the effects of early-life exposure to multiple specific ambient air pollutants on incidence and prevalence of asthma and to determine the mechanistic basis for these effects.
Methods: The study included all live-born singletons in Denmark during 1998-2016 (N = 1,060,154), participants in the Danish National Birth Cohort (DNBC, N = 22,084), and participants in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC, N = 803).
Article Synopsis
- * Using advanced statistical models, researchers analyzed data over a significant follow-up period, revealing that lung cancer incidence was positively linked to fine particulate matter (PM), nitrogen dioxide (NO₂), and black carbon (BC), while showing a negative association with ozone (O) which flipped after adjusting for NO.
- * The results indicated that the increased risk of lung cancer incidence was nearly as strong as that for mortality, with both associations remaining significant even at lower pollution levels, suggesting that air quality should be a crucial public health consideration.
End-stage kidney disease (ESKD) poses a high burden on patients and health systems. While numerous studies indicate an association between air pollution and chronic kidney disease, studies on ESKD are rare. We investigated the association of long-term exposure to nitrogen dioxide (NO₂), fine particulate matter (PM), black carbon (BC) and ozone (O) with ESKD incidence in two large population-based European cohorts.
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