Publications by authors named "B Brodie"
Chironomid nonbiting midges are common in many waterbodies, occurring at high densities in sediment and also when flying adults emerge. Although important for food webs and ecosystem processes, the mass emergences of chironomid adults make some species nuisance pests. As part of an effort to develop "push-pull" strategies for managing midge populations, we investigated the importance of visual and chemical cues used by gravid females when selecting sites for oviposition.
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- The study explored the relationship between high platelet reactivity (HPR) on clopidogrel and the risk of major adverse cardiac events (MACE) in patients undergoing coronary interventions, particularly focusing on those with diabetes mellitus (DM).
- Among the 8,582 patients in the study, it was found that HPR was more common in individuals with DM, and both groups (with and without diabetes) experienced increased rates of MACE linked to HPR.
- However, the impact of HPR on MACE risk differed based on diabetes type, with non-insulin-treated diabetes mellitus (non-ITDM) showing a stronger association compared to insulin-treated diabetes mellitus (ITDM).
Objectives: The purpose of this study was to assess the extent to which the association between premature dual antiplatelet therapy (DAPT) discontinuation and excess risk of thrombotic events varies according to the reason and timing of DAPT discontinuation and whether high on-treatment platelet reactivity (HPR) influences the risk of thrombotic events after premature DAPT discontinuation.
Background: DAPT after percutaneous coronary intervention (PCI) suppresses platelet reactivity, and HPR on clopidogrel after PCI is associated with an increased risk of thrombotic events.
Methods: ADAPT-DES (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents) was a prospective, multicenter registry of 8,582 patients successfully treated with coronary drug-eluting stents that assessed HPR on clopidogrel.
How organisms respond to variation in environmental conditions and whether behavioral responses can mitigate negative consequences on growth, condition, and other fitness measures are critical to our ability to conserve populations in changing environments. Offspring development is affected by environmental conditions and parental care behavior. When adverse environmental conditions are present, parents may alter behaviors to mitigate the impacts of poor environmental conditions on offspring.
View Article and Find Full Text PDFObjectives: The aim of this study was to determine the risk period for increased stent thrombosis (ST) after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS) and whether this increased risk is related to high platelet reactivity (HPR).
Background: ST risk after PCI is higher among patients with ACS than those with stable ischemic heart disease. When ST risk is highest in patients with ACS and how that is affected by HPR is unknown.