Comparison of the Ovary and Kidney as Sites for Islet Transplantation in Diabetic Rats.

Background: Currently, the most commonly used site for clinical islet transplantation is the liver although it is far from being an ideal site. Low oxygen tension and the induction of an inflammatory response impair islet implantation and lead to significant early loss of islet. The present study aimed to investigate and compare the efficacy of islet transplantation to the ovary and kidney subcapsule in diabetic rats.

Effect of stem cell application on Asherman syndrome, an experimental rat model.

Purpose: We evaluate the effect of stem cells to induce endometrial proliferation and angiogenesis on Asherman Syndrome (AS).

Methods: The experimental study was performed in stemcell research laboratory. Forty Wistar-Albino rats were divided according to groups.

Scintigraphic comparison of renal ischemia-reperfusion injury models in rats: correlations with biochemical and histopathological findings.

Objective: This study aimed to compare the effect on renal functions of ischemia-reperfusion (I-R) injury models by renal scintigraphy and to investigate possible correlations among scintigraphic, biochemical and pathological findings.

Methods: An experimental I-R injury was performed on the left kidneys of 40 Wistar rats: pedincular continuous clamping in Group 1 (n = 10), pedincular cyclic clamping in Group 2 (n = 10), arterial continuous clamping in Group 3 (n = 10) and arterial cyclic clamping in Group 4 (n = 10). A functional and morphological assessment was made by (99m)Tc-MAG3 scintigraphy, biochemical tests and histopathological examination in the late period of I-R injury.