All cultivated Patescibacteria, or CPR, exist as obligate episymbionts on other microbes. Despite being ubiquitous in mammals and environmentally, molecular mechanisms of host identification and binding amongst ultrasmall bacterial episymbionts are largely unknown. Type 4 pili (T4P) are well conserved in this group and predicted to facilitate symbiotic interactions.
View Article and Find Full Text PDFstrain BB002, was isolated from the human oral cavity on its basibiont bacterial host sp. oral taxon 171 strain F0337, related to . As a member of the within the candidate phylum radiation group (CPR), its reduced genome facilitates the survival as an ultrasmall (<0.
View Article and Find Full Text PDFIntroduction: Vitamin-K antagonists (VKA) are considered the first-line anticoagulants for thrombotic antiphospholipid syndrome (TAPS), particularly with triple positivity or arterial events. However, thrombotic recurrence remains high despite anticoagulation and other clinical issues may arise. Long-term parenteral anticoagulants may therefore be considered, however little is known about the viability of fondaparinux in this setting.
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