Publications by authors named "B Boonen"
Patient-specific instrumentation improved clinical outcome and implant survival but is not superior compared to conventional total knee arthroplasty: Ten years follow-up of a multicenter double-blind randomized controlled trial.
Knee Surg Sports Traumatol Arthrosc
October 2024
Article Synopsis
- ) Patient-specific instrumentation (PSI) was studied to see if it improves outcomes in total knee arthroplasty (TKA) compared to conventional instruments (CIs), but long-term results had been lacking.
- ) In a 10-year follow-up of a randomized controlled trial involving patients with knee osteoarthritis, both PSI and CI groups showed similar clinical outcomes and revision rates, with no significant differences.
- ) The study concluded that PSI did not provide better clinical outcomes or prosthesis survival compared to conventional methods over the 10-year period.
One in every three cancers diagnosed is a skin cancer. Europe has the global lead in the number of UV-attributable cancer cases with the highest number of melanoma cases worldwide and the second highest number of keratinocyte cancers (KC). Further increases are expected in Europe for the coming decades.
View Article and Find Full Text PDFIn order to understand protein function, the field of structural biology makes extensive use of cryogenic electron microscopy (cryo-EM), a technique that enables structure determination at atomic resolution following embedding of protein particles in vitreous ice. Considering the profound effects of temperature on macromolecule function, an important-but often neglected-question is how the frozen particles relate to the actual protein conformations at physiological temperatures. In a recent study, Hu et al.
View Article and Find Full Text PDFThis study investigates the intertwined processes of (anti-)apoptosis and cell proliferation in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Utilizing antibodies to Bcl-2 and Ki-67, the CD34-positive blast cell compartments in bone marrow aspirates from 50 non-malignant cases, 25 MDS patients, and 25 AML patients were analyzed for their anti-apoptotic and proliferative cell fractions through ten-color flow cytometry. MDS patients exhibited a significantly increased anti-apoptotic (p=0.
View Article and Find Full Text PDFPurpose Proximal humeral fractures (PHF) are common, particularly among the elderly due to low-energy trauma. Adequate rehabilitation is essential for functional recovery, whether through conservative or surgical treatment. Permissive weight bearing (PWB) is a relatively new rehabilitation concept, characterized by earlier mobilization of the affected limb/joint after trauma.
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