Publications by authors named "B Bonafos"

Polyphenols play a key role in the modulation of circadian rhythms, while the cafeteria diet (CAF) is able to perturb the hepatic biological rhythm and induce important ROS production. Consequently, we aimed to elucidate whether grape seed proanthocyanidin extract (GSPE) administration recovers the CAF-induced hepatic antioxidant (AOX) misalignment and characterize the chronotherapeutic properties of GSPE. For this purpose, Fischer 344 rats were fed a standard diet (STD) or a CAF and concomitantly treated with GSPE at two time-points (ZT0 vs.

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The increase in obesity has become a major global health problem and is associated with numerous metabolic dysfunctions. Furan fatty acids (FuFAs) are minor lipids present in our diet. Recently we showed that FuFA-F2 extracted from Hevea brasiliensis latex stimulates muscle anabolism in mice in vitro and in vivo, mimicking in part physical activity.

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Article Synopsis
  • Branched fatty acid esters of hydroxy fatty acids, specifically 9-PAHPA, were studied for their potential antidiabetic and anti-inflammatory effects in mice, showing improved insulin sensitivity when added to certain diets.
  • However, preventive supplementation with 9-PAHPA did not prevent significant weight gain or hyperglycemia in high fat and high sucrose diet mice, and in both diet-induced obesity (DIO) and db/db mice models, it had little impact on obesity or metabolic dysfunction.
  • Though 9-PAHPA improved insulin sensitivity in both DIO and db/db mice, it failed to affect body weight, fatty liver disease, or muscle at
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Palm oil (crude or refined) and lard are rich in SFA, while olive oil is rich in polyunsaturated fatty acids. SFA are considered harmful to health, while polyunsaturated fatty acids are beneficial to health. The aim of this study was to determine the effect of diets rich in crude PO, refined PO, OO, or lard on the mitochondrial membrane, the activity of mitochondrial respiratory chain complexes, and mitochondrial biogenesis.

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Palm olein (PO) and olive oil (OO) are widely consumed in the world. PO is considered harmful to health, whereas OO is considered healthy. The aim of the study was to compare the effects of consumption of these oils on antioxidant status and inflammation in rats.

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