A French Adaptation and Validation of Retirement Semantic Differential (RSD).

Retirement is associated with numerous representations, some of them being negative and the other positive. Yet, these representations affect the health of individuals in their transition to retirement. However, although the socio-political context in France favors the emergence of numerous representations of retired people, to our knowledge there is no scale validated in French that would allow us to evaluate them.

Smaller grey matter volume in the central olfactory system in mild cognitive impairment.

One of the major challenges in the diagnosis of Alzheimer's disease (AD) is to increase the specificity of the early diagnosis. While episodic memory impairment is a sensitive AD marker, other measures are needed to improve diagnostic specificity. A promising biomarker might be a cerebral atrophy of the central olfactory processing areas in the early stages of the disease since an impairment of olfactory identification is present at the clinical stage of AD.

Olfaction and declarative memory in aging: a meta-analysis.

Olfactory and declarative memory performances are associated, as both functions are processed by overlapping medial-temporal and prefrontal structures and decline in older adults. While a decline in olfactory identification may be related to a decline in declarative memory, the relationship between olfactory detection threshold and declarative memory remains unclear. In this meta-analysis, we assessed (i) the relationship between olfactory identification/detection threshold and verbal declarative memory in cognitively normal older adults, and (ii) the effect of age on these relationships.

Diagnostic Sensitivity and Specificity of Cognitive Tests for Mild Cognitive Impairment and Alzheimer's Disease in Patients with Down Syndrome: A Systematic Review and Meta-Analysis.

Background: Improved health care for people with Down syndrome (DS) has resulted in an increase in their life expectancy therefore increasing comorbidities associated with age-related problems in this population, the most frequent being Alzheimer's disease (AD). To date, several cognitive tests have been developed to evaluate cognitive changes related to the development of mild cognitive impairment (MCI) and AD in people with DS.

Objective: Identify and evaluate available cognitive tests for the diagnosis of MCI and AD in people with DS.