Background And Objective: Patients with chronic HIV infection face a high risk of premature coronary atherosclerosis, partly due to continuous HAART therapy and susceptibility to opportunistic infections, complicating percutaneous coronary intervention (PCI). HIV patients have unique coronary vasculature characteristics. This study aimed to assess the clinical outcomes of PCI using the novel tapered sirolimus-eluting coronary stent (SES) system in HIV patients.
View Article and Find Full Text PDFPediatric obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by upper airway obstruction during sleep, leading to oxygen desaturation and sleep disruptions. This comprehensive review examines the epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, consequences, management strategies, challenges, and future directions of pediatric OSA. Prevalence rates vary globally, with notable associations found between OSA and obesity.
View Article and Find Full Text PDFBackground: NHS England issued commissioning guidance on 18 low-priority treatments which should not be routinely prescribed in primary care. We aimed to monitor the impact of an educational intervention delivered to regional prescribing advisors by senior pharmacists from NHS England on the primary care spend on low-priority items.
Methods: An opportunistic randomised, controlled parallel-group trial.
Tuberculosis (TB) remains a significant global health concern, particularly in high-burden countries. Pleural involvement, such as pleural thickening and trapped lung, is a common complication of tuberculous empyema, often leading to respiratory compromise and reduced quality of life. In this case report, a 58-year-old male farmer presented with progressive breathlessness and orthopnea, indicative of pleural pathology.
View Article and Find Full Text PDFSecondary spontaneous pneumothorax (SSP) is one of the rare and crucial complications of pulmonary tuberculosis (TB) and can become a fatal condition if it progresses to tension pneumothorax. This case report describes a 32-year-old male who presented with sudden onset chest pain and shortness of breath for the past three hours. On examination, he exhibited tachypnea and hypoxia at rest, and chest imaging revealed a right-sided pneumothorax.
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