Ruthenium-catalyzed electrochemical C-H activation of benzamidine hydrochlorides with internal alkynes for the synthesis of 1-aminoisoquinolines.

A constant current electrochemical approach for the synthesis of 1-aminoisoquinoline derivatives through the Ru(II)-catalyzed annulation of benzamidine hydrochlorides with alkynes is reported herein. This method produces good yields of naphthyridine-based compounds Ru(II)-catalyzed C-H bond cleavage, leading to the formation of new C-C and C-N bonds in a one-pot manner. Notably, the synergy of electricity and Ru catalysis offers broad reaction compatibility, accommodating a wide range of substrates with diverse steric and electronic properties.

Pd-catalysed synthesis of oxomalonamides through adjacent triple carbonylation of tertiary amines.

The monocarbonylation and dicarbonylation reactions are well-established reactions in carbonylation chemistry. This work reports unusual oxidative adjacent triple carbonylation of the tertiary amine towards oxomalonamide synthesis using a Pd catalyst. The protocol involves the use of inert tertiary amines as an active reservoir of secondary amines through sp C-N bond activation using O as an ideal oxidant.

The synthesis of alk-2-ynl Weinreb amides Pd/Cu-catalysed oxidative carbonylation of terminal alkynes.

Synthesis of alk-2-ynl-Weinreb amides Pd-catalyzed oxidative carbonylation of terminal alkynes and ,-dimethylhydroxylamine hydrochloride at room temperature under low CO/O pressure is reported for the first time. This protocol offers tolerance of various functional groups under mild reaction conditions. The protocol incorporates aromatic- and aliphatic-substituted alkynes through a one-step oxidative carbonylative route toward desired alkynyl Weinreb amides, which are of considerable importance as valuable synthetic building blocks.

Improved biocatalytic activity of steapsin lipase in supercritical carbon dioxide medium for the synthesis of benzyl butyrate: A commercially important flavour compound.

Enzymatic synthesis of flavours, fragrances and food additives compounds have great demand and market value. Benzyl butyrate is commercially important flavour and food additive compound having global use around 100 metric tons/year and widely used in various industrial sectors. However, industrial synthesis of food additive benzyl butyrate is carried out by conventional chemical process which demands for the green biobased sustainable synthetic process.

Particle shape anisotropy in pickering interfacial catalysis for Knoevenagel condensation.

Dispersions of two immiscible liquids stabilized by solid particles are termed as Pickering emulsions. Stability of such emulsions is affected by various parameters such as amount of solid particle, method of emulsification, size, and shape of particles, etc. In this study, MgO samples prepared by different methods and characterized by XRD, FESEM, HRTEM, DLS, and CO-TPD techniques were utilized for stabilizing o/w Pickering emulsions.