Publications by authors named "B Bercot"
Background And Objectives: Diagnosing ventriculostomy-related infection (VRI), a common complication after external ventricular drainage (EVD), is challenging and often associated with delayed initiation of antibiotic therapy. We aimed to develop a stewardship score to help in the decision of antibiotic therapy initiation when VRI is suspected.
Methods: This retrospective, single-center cohort study included patients admitted to the intensive care unit after EVD placement who were suspected of having healthcare-associated ventriculitis and/or meningitis between January 1, 2012, and August 31, 2022.
Purpose: To describe the relationships between Neisseria meningitidis (NM) and Neisseria gonorrhoeae (NG) at genetic, population, and individual levels; to review historical trends in antimicrobial resistance (AMR); to review the treatment and preventive landscapes and explore their potential impact on AMR.
Methods: A narrative literature search was conducted in PubMed, with searches restricted to 2003-2023 and additional articles included based on expertise.
Results: NM and NG are closely related bacterial pathogens causing invasive meningococcal disease (IMD) and gonorrhea, respectively.
Article Synopsis
- Since 2022, Europe has identified 4 cases of extensively drug-resistant Neisseria gonorrhoeae, particularly sequence type 16406, which is resistant to ceftriaxone and has high resistance to azithromycin.
- In 2023, two new related cases were reported in France that share genetic links with the previous European cases and strains from Cambodia.
- This highlights growing concerns about the spread of drug-resistant gonorrhea in Europe and its potential global implications.
Background: Varicella zoster virus (VZV) can reactivate and cause meningitis, but few studies have distinguished it from meningoencephalitis regarding treatment recommendations.The objective of this study was to assess the outcomes of a large series of patients with VZV meningitis according to their therapeutic management.
Methods: We conducted a bicentric retrospective cohort study, in Paris, France, including all adult patients with a cerebrospinal fluid sample positive for VZV by polymerase chain reaction between April 2014 and June 2022.