Publications by authors named "B Beland"

Objectives: Patients with refractory myasthenia gravis (MG) have few treatment options. Autologous hematopoietic stem cell transplantation (HSCT) has been used to treat immune diseases; however, its use in the treatment of MG is not broadly considered. Our objective is to report on the efficacy and safety of HSCT in refractory MG.

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Background: The presence of an intraluminal thrombus in acutely symptomatic carotid stenosis is thought to represent a high-risk lesion for short-term stroke reccurrence though evidence on natural history and treatment is lacking, leading to equipoise and much variation in practice. The objective of this study was to map these variations in practice (medical management and timing of revascularization), determine the considerations that influence clinician decision-making in this condition and gather opinions that inform the development and design of future trials in the area.

Methods: This was a mixed-methods study using both quantitative survey methods and qualitative interview-based methods.

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Article Synopsis
  • * A retrospective analysis of 179 gMG patients from the University of Calgary found that the likelihood of starting treatment and the time from diagnosis to treatment initiation did not differ between sexes when accounting for various factors.
  • * The findings suggest that the differences in quality of life seen in females with gMG are not related to treatment initiation, indicating that further research should focus on exploring physician and patient preferences in treatment strategies.
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