Publications by authors named "B Batchelor"
Article Synopsis
- The study examines the long-term quality-of-life (QoL) outcomes for older adults (65+) with stable ischemic heart disease (SIHD) and diabetes after different treatment methods: intensive medical therapy (IMT) alone, revascularization (PCI or CABG) with optimal medical therapy (OMT).
- A total of 929 patients were analyzed over five years, revealing no significant differences in QoL metrics such as self-health score and Duke activity status index (DASI) between those who underwent PCI or CABG compared to those who received IMT alone.
- The findings suggest that both treatment approaches lead to similar QoL outcomes, highlighting the need for more targeted research in older adults regarding SIHD treatment, especially
Tauopathy is characterized by neuronal dysfunction and degeneration occurring as a result of changes to the microtubule-associated protein tau. The neuronal changes evident in tauopathy bear striking morphological resemblance to those reported in models of Wallerian degeneration. The mechanisms underpinning Wallerian degeneration are not fully understood although it can be delayed by the expression of the slow Wallerian degeneration (Wld) protein, which has also been demonstrated to delay axonal degeneration in some models of neurodegenerative disease.
View Article and Find Full Text PDFA novel aerator for enhancing the oxygen transfer rate and efficiency, named multistage vortex aerator (MVA), was developed. It uses vortex flow in repeated stages to increase the gas-liquid interfacial area and to decrease the thickness of the stagnant layer at the interface between the two phases. The basic characteristics of oxygen transfer using this aerator were investigated using the American Society of Civil Engineers standard procedure.
View Article and Find Full Text PDFBackground: Serological assays are being used to monitor antibody responses in individuals who had SARS-CoV-2 infection and those who received a COVID-19 vaccine. We aimed to determine whether such assays can predict neutralising antibody titres as antibody levels wane and viral variants emerge.
Methods: We measured antibody levels in serum samples from a cohort of 112 participants with SARS-CoV-2 infection using ten high-throughput serological tests and functional neutralisation assays.
SARS-CoV-2 antibody tests have been marketed to diagnose previous SARS-CoV-2 infection and as a test of immune status. There is a lack of evidence on the performance and clinical utility of these tests. We aimed to carry out an evaluation of 14 point of care (POC) SARS-CoV-2 antibody tests.
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