[Predictive value of urinary cytology in the diagnosis of urothelial tumors].

Between November 1991 and June 1993, 315 patients with urethral lesions were divided into two groups: group 1 included 215 patients with urethral tumours and group 2 included 100 patients with non-tumoural lesions. In all patients, urethral smears (performed on 3 consecutive days), pyelography and uretrocystoscopy (with bladder biopsy of observable lesions) were performed in all. The sensitivity of urine cytology examinations in the diagnosis of bladder cancer was found to by 80% with a specificity of 90%.

Dynamics of human sperm acrosome reaction: relation with in vitro fertilization.

Objective: Acrosomal status has been studied on human sperm prepared for in vitro fertilization (IVF) and related to the rate of fertilization.

Design And Patients: A group of 41 men with normal classical semen parameters, included in the IVF program of University of Nice for feminine tubal obstruction (n = 37) or unexplained infertility (n = 4), were evaluated in a prospective study and compared with a control group of 10 fertile donors.

Main Outcome Measures: Evaluation of acrosome status (spontaneous and A23187-induced acrosome loss) after 6 hours incubation in Ménézo's B2 medium was made by flow cytometry on suspended cells with a new immunofluorescence test recently reported by the authors based on a monoclonal antibody GB24.

[Comparative cytogenetic study of 7 types of mammary cancer].

Cytogenetic analysis of 58 cells originating in 7 mammary carcinomas indicated the existence of characteristic numerical and structural modifications, concerning the long arm of chromosome 1, chromosomes 4, 5, 7, 14, 15 and X, and the short arm of chromosome 16. Establishing the alterations of chromosomal "markers" could not only depend on selective phenomena relating to modifications of the genome but also on the preferential reassociations of heterochromatic segments.