Immunolocalization of intercellular adhesion molecule-1 and leukocyte functional associated antigen-1 in schistosomal soluble egg antigen-induced granulomatous hyporesponsiveness.

In this work, the changes in expression of the adhesion molecules ICAM-1/LFA-1 on inflammatory cells of the liver were studied by immunohistochemistry. Mice sensitized with SEA and infected with S. mansoni and S.

Immunolocalization of macrophage adhesion molecule-1 and macrophage inflammatory protein-1 in schistosomal soluble egg antigen-induced granulomatous hyporesponsiveness.

This work studied the histopathological changes and the changes in the expression of macrophage adhesion molecule-1 (Mac-1) and macrophage inflammatory protein-1alpha (MIP-1alpha) in a murine model of soluble egg antigen (SEA) - induced granulomatous hyporesponsiveness. Histopathological results of hepatic sections in an SEA group showed early acceleration of ova destruction and markedly diminished granuloma cellularity with eosinophils and macrophages still being the predominant cells. Later, giant cells and pigmented macrophages that were scattered among granuloma cells and in intimate contact with the deposited eggs were more predominant in the SEA group than in the infected control group.

Continuous ST-segment monitoring during coronary angioplasty using orthogonal ECG leads.

In order to characterize ST-segment shifts during transient coronary artery occlusion, 24 patients with single-vessel disease were continuously monitored during percutaneous transluminal coronary angioplasty by use of a computerized orthogonal lead system. Changes of ST-segment (J + 60 ms) in leads X, Y, and Z and of the ST vector magnitude were analyzed by using 20 microV as a threshold for significant ST-segment shift. The sensitivity and magnitude of this shift were compared among the left anterior descending, right coronary, and circumflex artery groups (11, 8, and 5 patients, respectively) during balloon inflation.

Continuous ST segment recording during thrombolysis in acute myocardial infarction: a report on orthogonal ECG monitoring.

Background: A noninvasive, real time method is needed to identify failures of thrombolysis and evaluate new treatments in acute myocardial infarction (MI).

Objective: To study XYZ monitored ST segment evolution during thrombolysis in acute MI and to examine the correlation of ST parameters to outcome.

Design: Thirty-five patients receiving tissue plasminogen activator (tPA) (n = 18) or streptokinase (SK) (n = 17) for acute MI were monitored by vector-cardiography during the first 12 h of thrombolytic therapy.

Fluorescence microscopy in the detection of early myocardial infarction.

Fluorescent microscopy is amongst the many techniques devised for the post-mortem detection of early myocardial infarction. The method has the advantage of sensitivity, speed and simplicity, compared with more complex techniques such as enzyme histochemistry and electron microscopy. Disadvantages include the difficulty of permanent preservation of the sections and lack of sharp differentiation between normal and very early infarction--though the latter problem is common to most other methods, except enzyme histochemistry.