Publications by authors named "B Bachman"
Article Synopsis
- Thalamo-cortical networks play a crucial role in seizures, but the exact mechanisms behind their initiation are still unclear.
- This study investigates the ventral posteromedial nucleus (VPM) of the thalamus as a potential source of generalized convulsive motor seizures, using an in vivo optogenetic mouse model to examine thalamic neuron activity during seizures.
- Findings suggest that diverse neural activity in the VPM, along with significant contributions from inputs like the cerebellum, is essential for seizure initiation, with lidocaine injections into cerebellar nuclei effectively blocking the seizures.
Stressful events can have lasting and impactful effects on behavior, especially by disrupting normal regulation of fear and reward processing. Accurate discrimination among environmental cues predicting threat, safety or reward adaptively guides behavior. Post-traumatic stress disorder (PTSD) represents a condition in which maladaptive fear persists in response to explicit safety-predictive cues that coincide with previously learned threat cues, but without threat being present.
View Article and Find Full Text PDFSolvated electrons in water have long been of interest to chemists. While readily produced using intense multiphoton excitation of water and/or irradiation with high-energy particles, the possible role of solvated electrons in electrochemical and photoelectrochemical reactions at electrodes has been controversial. Recent studies showed that excitation of electrons to the conduction band of diamond leads to barrier-free emission of electrons into water.
View Article and Find Full Text PDFArticle Synopsis
- Researchers are exploring the functionalization of diamond surfaces with TEMPO and other paramagnetic species to enhance chemical detection using quantum color defects like SiV and NV centers.
- Previous methods struggled with effective surface functionalization, but this study demonstrates a well-controlled technique using carboxylic acid groups linked by carbon tethers to create high-quality TEMPO-modified diamond surfaces.
- The study reports a higher surface density of TEMPO on nanodiamond (1.4 molecules/nm) and planar diamond (3.3 molecules/nm) compared to previous techniques, while using ζ-potential to monitor reaction progress and identify reaction selectivity.