Publications by authors named "B Baban"
Emerging evidence suggests that aberrant expression levels of Sigma1 (, also known as sigma-1 receptor) have been implicated in the progression of various diseases, including cancer. However, its significance in oral cancer (OC) has not been thoroughly explored. To advance in this field, the present study aimed to investigate the impact of knockdown in oral cancer cells.
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- Ischemic stroke can lead to severe disability and death, and researchers are investigating how the timing of a stroke impacts its severity, particularly focusing on the circadian clock protein Rev-Erbα.
- A study found that administering SR9009, a Rev-Erbα agonist, significantly reduced neuroinflammation and infarct size in mice when treated at specific times (ZT06 - during sleep) but not at other times (ZT18 - during wakefulness).
- The results suggest that SR9009 alters immune responses and may offer therapeutic benefits for stroke treatment, emphasizing the importance of timing in administering interventions.
Alzheimer's disease (AD) is a challenging medical issue that requires efficacious treatment options to improve long-term quality of life. Cannabidiol (CBD) is a cannabis-derived phytocannabinoid with potential health benefits, including reports from our laboratory and others showing a therapeutic role in the pre-clinical treatment of AD; however, the mechanisms whereby CBD affects AD progression remain undefined. Innate lymphoid cells (ILCs) are recently discovered immune cells that initiate and orchestrate inflammatory responses.
View Article and Find Full Text PDFCutaneous wounds, both acute and chronic, begin with loss of the integrity, and thus barrier function, of the skin. Surgery and trauma produce acute wounds. There are 22 million surgical procedures per year in the United States alone, based on data from the American College of Surgeons, resulting in a prevalence of 6.
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- Glioblastoma (GBM) is a highly aggressive brain tumor associated with high mortality rates, and this study explores the role of the FAM3C gene in GBM through bioinformatics analysis.
- Researchers analyzed transcriptomic data to reveal that high levels of FAM3C are linked to poor survival outcomes in GBM patients and identified FAM3C as crucial for several cancer characteristics.
- The study also discovers a relationship between high FAM3C expression and increased immune cell abundance, suggesting FAM3C could serve as a valuable biomarker for GBM and offers insights for future research directions.