[The clinical trial of a Russian membrane plasma filter in patients under therapy].

35 procedures of plasmofiltration were conducted on the test series of domestic membrane plasmofilter in 25 patients suffering from atopic diseases, systemic affections of connective tissue, advanced atherosclerosis, etc. The filter proved promising in therapeutic patients. The procedure is easier to perform compared to centrifuge plasmapheresis, it can work under thin blood flow.

[Control of hypoxia using apneic oxygenation with extrapulmonary membrane elimination of CO2].

The peculiarities and conditions of optimal gas exchange for arresting hypoxia during prolonged (3 hours) apnoea or bradypnoea were experimentally studied in 34 dogs, using the method of apnoea oxygenation and extrapulmonary membrane removal of CO2 on "Sever" membrane gas-exchanger. It was shown that successful arrest of severe ventilation disorders of respiration by this method depends on precise registration and skillful use of the factors influencing oxygenation and CO2 removal in membrane gas-exchanger connected with peripheral arteriovenous or venovenous shunts.

[Effect of the mode of extrapulmonary gas exchange on the function and metabolism of pulmonary surfactant].

The peculiarities of the functional state of lung surfactant as well as the character and degree of disorders in its phospholipid metabolism during venoarterial perfusion and extrapulmonary 120-min oxygenation carried out with the help of contact-type (foam-film) and membrane ("Sever") oxygenators were studied in 28 experimental dogs. It was shown that the functional state and phospholipid metabolism of lung surfactant were strongly dependent on the mode of extrapulmonary gas exchange (the type of oxygenator). Membrane oxygenation is more physiological than contact-type gas exchange.