Hepatic and Pancreatic Cellular Response to Early Life Nutritional Mismatch.

To determine the basis for perinatal nutritional mismatch causing metabolic dysfunction associated steatotic liver disease (MASLD) and diabetes mellitus, we examined adult phenotype, hepatic transcriptome, and pancreatic β-islet function. In prenatal caloric restricted rat with intrauterine growth restriction (IUGR) and postnatal exposure to high fat with fructose (HFhf) or high carbohydrate (RC), we investigated male and female IUGR-Hfhf and IUGR-RC, versus HFhf and CON offspring. Males more than females displayed adiposity, glucose intolerance, insulin resistance, hyperlipidemia, hepatomegaly with hepatic steatosis.

Impact of Multidrug-Resistant Bacterial Colonization on Clinical Characteristics, Antibiotic Treatment, and Clinical Outcomes of Hospital-Acquired Pneumonia.

Purpose: To determine effects of colonization with multidrug-resistant bacteria (MDRB) in general wards on characteristics, treatment, and prognosis of hospital-acquired pneumonia (HAP).

Methods: This was a multicenter retrospective cohort study of patients with HAP admitted to 16 tertiary or university hospitals in Korea from July 2019 to December 2019. From the entire cohort, patients who developed pneumonia in general wards with known colonization status before the onset of pneumonia were included in this study.

Characteristics and direct causes of death in severely ill patients admitted to a neurology department.

Introduction: The study aimed to analyze the characteristics of patients admitted to the neurology department of a tertiary hospital who subsequently died, focusing on those with high disease severity.

Materials And Methods: We conducted a retrospective cohort study of patients who died among those admitted to the neurology department of a regional tertiary hospital from 2013 to 2021. Clinical, radiological, and laboratory results of the included patients were collected, and their primary diagnoses, duration from time of admission to death, and direct causes of death were analyzed.

Qigong Therapy for Stress Management: A Systematic Review of Randomized Controlled Trials.

Background/objective: Althouth Qigong is commonly used to manage stress, anxiety, and depression, there have been no systematic reviews on Qigong therapy for stress management. This study aimed to analyze the clinical evidence of Qigong therapy for perceived stress.

Methods: We conducted a systematic search for randomized controlled trials (RCTs) of Qigong using 11 electronic databases, namely MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Physiotherapy Evidence Database, CINAHL, and Korean Medical databases (Korea Institute of Science and Technology Information, Korean traditional knowledge portal, KoreaMed, OASIS, RISS, and the National Library of Korea).

ICRP pregnant-female mesh-type reference computational phantoms part 1: development of fetal phantoms.

. The International Commission on Radiological Protection (ICRP) decided to develop pregnant-female reference computational phantoms, including the maternal and fetal phantoms, through its 2007 general recommendations. Acknowledging the advantages of the mesh geometry, the ICRP decided to develop the pregnant-female mesh-type reference computational phantoms (MRCPs) for 8, 10, 15, 20, 25, 30, 35, and 38 week fetal ages directly in the mesh format.