Publications by authors named "B B Matsubara"
Article Synopsis
- Bioimpedance spectroscopy (BIS) is a non-invasive technique for assessing fluid volumes, specifically used to compare measurements between heart failure (HF) patients and healthy individuals.
- In a study of 64 HF patients and 69 healthy controls, significant differences were found in extracellular fluid percentage relative to total body water (ECF%TBW), suggesting altered fluid distribution in HF patients.
- The findings indicate that BIS can help classify fluid status in HF patients into normal, elevated, or fluid overload categories, aiding in their clinical management and risk assessment.
Purpose: The aim of this study was to compare the effects of supervised combined physical training and unsupervised physician-prescribed regular exercise on the functional capacity and quality of life of heart failure patients.
Methods: This is a longitudinal prospective study composed of 28 consecutive heart failure with reduced ejection fraction patients randomly divided into two age- and gender-matched groups: trained group ( = 17) and nontrained group ( = 11). All patients were submitted to clinical evaluation, transthoracic echocardiography, the Cooper walk test, and a Quality of Life questionnaire before and after a 12-week study protocol.
Background: Brain death elicits microvascular dysfunction and inflammation, and thereby compromises lung viability for transplantation. As 17β-estradiol was shown to be anti-inflammatory and vascular protective, we investigated its effects on lung injury after brain death in male rats.
Methods: Wistar rats were assigned to: sham-operation by trepanation only (SH, n = 7); brain death (BD, n = 7); administration of 17β-estradiol (280 μg/kg, iv) at 60 minutes after brain death (BD-E2, n = 7).
Background: Coronary artery disease is present in at least 30% of patients with degenerative aortic stenosis (AS). Atherosclerosis also performs an important role in the progression of AS, because of the similarities of pathological mechanisms in both conditions. The electrocardiogram (EKG) strain pattern is associated with structural myocardial change and subendocardial ischemia and has been worldwide used as a marker of AS severity.
View Article and Find Full Text PDFAcute doxorubicin-induced cardiotoxicity is associated with matrix metalloproteinase-2 alterations in rats.
Cell Physiol Biochem
December 2015
Background: Doxorubicin can cause cardiotoxicity. Matrix metalloproteinases (MMP) are responsible for degrading extracellular matrix components which play a role in ventricular dilation. Increased MMP activity occurs after chronic doxorubicin treatment.
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