Ternifoliasaponin, a new triterpenoid saponin from the roots of Schumach & Thonn (Rubiaceae).

A new triterpenoid saponin, Ternifoliasaponin (), together with four known compounds () chikusetsusaponin IVa (), chikusetsusaponin IVa methyl ester (), bonushenricoside B ) and Dianoside C () were isolated from roots of Schumach. & Thonn (Rubiaceae). The structures of isolated compounds were elucidated on the basis of spectroscopic analysis and chemical methods.

Antioxidant Potential and Improvement Activities of Delile on Insulin Resistance in Type 2 Diabetic Rats Induced by High-Fat Diet and Low Dose of Streptozotocin.

Background: is widely used in traditional medicine throughout the world. Ethnobotanical surveys have revealed its use to handle diabetes. This present research investigated the antioxidant potential and improvement activities of Delile on insulin resistance in type 2 diabetic rats.

Hydromethanolic Root Extract of Gnidia Kraussiana Demonstrates Anti-Inflammatory Effect Through Anti-Oxidant Activity Enhancement in a Rodent Model of Gout.

Gout is a metabolic arthritis that originates from increased accumulation of monosodium urate (MSU) crystals in joints. This work aimed to evaluate the antioxidant and anti-inflammatory activities of the hydromethanolic extract of (HEGK) using model of Gouty arthritis on mice. The total polyphenol, flavonoid, tannin content and the antioxidant activity of HEGK were also evaluated.

Antifilarial Activity of the Methanolic Extract of (Fabaceae) on Bovine Parasites ().

Onchocerciasis is a major public health problem caused by parasite and transmitted to humans via black flies ( bites. The control of onchocerciasis relies much on the use of the chemical drug ivermectin, which is only effective against microfilariae and has led to drug resistance. This study was carried out to assess the antifilarial activity of methanolic extract of and its most active fractions on adult male worm, the closest model to , after 48 h and 72 h of treatment.

Antioxidant Mechanism of Renal and Hepatic Failure Prevention Related to Paracetamol Overdose by the Aqueous Extract of Stem Bark.

Paracetamol is a commonly used analgesic/antipyretic whose long-term intake or overdose is associated with renal and hepatic injuries. The aim of this study was to determine the hepatonephroprotective mechanisms of the aqueous extract of stem bark (AEAASB) on renal and hepatic failure resulting from paracetamol overdose. Forty-five rats were divided into nine groups ( = 5); these were treated once daily for 8 days with 5 ml/kg distilled water (normal, negative, and satellite controls); 0.