Publications by authors named "B B Kostishko"

Unlabelled: Hyperbaric oxygenation (HBO) for correction of platelet haemostasis disorders in coronary heart disease (CHD) is reasonable due to the associated hypocoagulation. However, in practice, the baseline state of platelet activity is not considered when prescribing HBO therapy. Available publications lack information on structural changes in the platelet membrane associated with the of phospholipase A2 (PLA2) activity, and on the HBO effect on the various steps of hemostasis.

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Background: The authors present evidence of the significance and role of the disturbances in platelet hemostasis in pathogenesis of co-morbid cardiac pathology and the absence of the unambiguous opinion as regards the expediency of the application of hyperbaric oxygenation (HBO) for their correction which implies the necessity of searching for new pathogenetically substantiated approaches to the treatment of the patients presenting with this condition.

Aim: The objective of the present study was to evaluate the influence of hyperbaric oxygenation on the elastic properties of platelet membrane during spontaneous platelet aggregation in the patients presenting with cardiac co-morbidity.

Material And Methods: Thrombocyte hemostasis was investigated in 24 patients at the age of 52.

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Aim: To study the efficacy of a current regimen of treatment with cavinton for infusions and cavinton comforte in patients with ischemic stroke in acute and early recovery periods and to evaluate an impact of treatment on erythrocyte deformity using atomic power microscopy.

Material And Methods: One hundred and sixty-four patients with hemispheric ischemic stroke, aged from 30 to 79 years, were randomized into main (n=100) and control (n=64) groups. Patients of the main group received complex treatment (basic therapy and cavinton R for drop infusions (10 intravenously during 10 days) followed by cavinton R comforte in dose 10 mg, 1 tablet 3 times a day during 90 days).

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Objective: To study the effect of vasonit on the structural/functional state of erythrocyte cytoplasmic membrane in patients with ischemic stroke (11) using atomic-power microscopy in vitro.

Material And Methods: We examined 45 patients with II. Patients of the main group (n=30) received vasonit and standard treatment, 15 patients of the comparison group received only standard treatment.

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