Publications by authors named "B B Ganesh"

A novel Schiff base ligand (L), bearing NO donor sites, was derived from the condensation of 5-chloromethylisophthaldehyde and phenylpropanolamine (PPA). Mononuclear Co(II), Cu(II), and Zn(II) complexes were synthesized and were characterized by FTIR, UV-Vis, H NMR, ESI-mass spectroscopy, molar conductance, and thermal and electrochemical studies. The thermal investigation revealed that the complexes were stable up to 150-250 °C and began to degrade in stages, resulting in the development of respective metal oxides.

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  • Alzheimer's disease (AD) is more prevalent in women than in men, with factors beyond longevity, like metabolic changes, influencing this increased risk.
  • A study conducted metabolomic profiling of blood samples from male and female patients with mild cognitive impairment (MCI), revealing significant metabolic differences related to sex, particularly in lipid and peptide energy metabolism pathways.
  • The research identified specific metabolites unique to each sex, such as higher levels of 1-palmitoleoyl glycerol in females, suggesting these could be potential biomarkers to enhance our understanding of MCI and AD prevention strategies.
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Alzheimer's disease (AD) affects more women than men. Although women live longer than men, it is not longevity alone, but other factors, including metabolic changes, that contribute to the higher risk of AD in women. Metabolic pathways have been implicated in AD progression, but studies to date examined targeted pathways, leaving many metabolites unmeasured.

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  • * Research indicates that older mothers' gut microbiomes negatively impact pregnancy outcomes and offspring behavior, even when young mice are recolonized with the microbiome of older females before pregnancy.
  • * The study found that offspring from these older microbiome recolonized mothers exhibited increased fetal loss, persistent changes in gut microbiome composition, and developed anxiety- and depression-like behaviors, suggesting a link between maternal microbiome changes and neuropsychiatric risks in children.
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Background: The left ventricle segmentation (LVS) is crucial to the assessment of cardiac function. Globally, cardiovascular disease accounts for the majority of deaths, posing a significant health threat. In recent years, LVS has gained important attention due to its ability to measure vital parameters such as myocardial mass, end-diastolic volume, and ejection fraction.

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