Publications by authors named "B Assouline"
Purpose: Fever is frequent after extracorporeal membrane oxygenation (ECMO) decannulation. We aimed to evaluate the incidence of post-decannulation fever and describe its causes.
Methods: Adult ECMO patients who were successfully weaned from ECMO were retrospectively included.
Senescent cells within tumors and their stroma exert complex pro- and anti-tumorigenic functions. However, the identities and traits of these cells, and the potential for improving cancer therapy through their targeting, remain poorly characterized. Here, we identify a senescent subset within previously-defined cancer-associated fibroblasts (CAFs) in pancreatic ductal adenocarcinomas (PDAC) and in premalignant lesions in mice and humans.
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- High-risk pulmonary embolism (PE) patients can experience hemodynamic instability despite treatment; VA-ECMO is explored as a life-saving intervention, but pre-treatment with systemic thrombolysis poses risks of bleeding.
- A study covering 72 patients assessed ECMO complications and survival rates, revealing similar 90-day survival rates and bleeding incidents between those treated with systemic thrombolysis and those without.
- Long-term quality of life for survivors was found to be acceptable, indicating that recent systemic thrombolysis shouldn't be deemed a contraindication for VA-ECMO in high-risk PE cases.
Article Synopsis
- Right ventricular failure (RVF) is a critical issue leading to high mortality rates shortly after heart transplantation, and the study explores how isoproterenol (Iso) can help improve heart function in these patients.
- A retrospective study over one year evaluated the hemodynamic effects of Iso in 25 patients with early RVF, comparing no Iso treatment to low and high doses of Iso.
- Results showed that Iso significantly increased heart rate and cardiac index, indicating improved heart function, while its effects on pulmonary pressures were minimal, highlighting its potential as a beneficial treatment for RVF post-heart transplant.