Publications by authors named "B Asfaw"
Several strains of parasite are involved in the occurrence of leishmaniasis infections, which makes its prevention and treatment very challenging. Currently, all forms of leishmaniasis are being treated with chemical drugs, which have limitations and adverse effects. Discovering antileishmanial agents from natural sources can lead to novel drugs against this dreadful disease.
View Article and Find Full Text PDFIntroduction: Toxicity and resistance to chemotherapy used to treat leishmaniasis are increasing. Research on natural plant compounds has revealed their antileishmanial effects on certain Leishmania organisms. This review aimed to estimate the pooled IC50 values of medicinal plants with promising antileishmanial activity in Ethiopia.
View Article and Find Full Text PDFArticle Synopsis
- Black cumin seed oil is recognized for its medicinal and aromatic properties, with studies indicating variability in oil content and yield among different genotypes in Ethiopia.
- A study involving 64 Ethiopian genotypes assessed biochemical traits, with significant differences found in fixed oil yield, essential oil content, and yield, indicating potential for selection to enhance these traits.
- Principal component analysis showed that the first two components captured nearly 86% of the variance, with genotypes demonstrating sufficient diversity that can be leveraged for further improvements in oil production.
Background: Fabry disease (FD) is an X-linked lysosomal storage disease resulting from pathogenic variants in the GLA gene coding α-galactosidase A (AGAL) and cleaving terminal alpha-linked galactose. Globotriaosylceramide (Gb3) is the predominantly accumulated sphingolipid. Gb3, deacylated-Gb3 (lysoGb3), and methylated-Gb3 (metGb3) have been suggested as FD biomarkers.
View Article and Find Full Text PDF