Publications by authors named "B Ascott-Evans"

Background: Urine dipstick testing for ketones is widely used when diabetic ketoacidosis (DKA) is suspected in patients with hyperglycaemia. If urinary ketones are positive, patients are referred for further management--often inappropriately, as the test is a poor surrogate for plasma ketones. Plasma beta-hydroxybutyrate (β-OHB) levels>3 mmol/L are diagnostic of DKA, while levels<1 mmol/L are insignificant.

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Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), are increasingly being used by psychiatric patients. Most studies have concentrated on efficacy aspects, while little is known about their safety and tolerability in psychiatric populations. This study aimed to assess the effects of EPA treatment on body mass, glucose metabolism, lipid profiles, prolactin secretion, bleeding time, haematology and liver functions.

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Article Synopsis
  • Hormone therapy helps prevent bone loss during menopause, but is not advised after symptoms resolve, leading to rapid bone loss when discontinued.
  • A review of studies showed a significant decline in bone mineral density (BMD) within the first year after stopping hormone therapy, with drops between 2.3% and 6.2%.
  • Alendronate is an effective treatment option to prevent bone loss after discontinuation, significantly increasing BMD in women with low bone density who recently stopped hormone therapy.
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