Publications by authors named "B Arumugam"
Article Synopsis
- The study investigates how Peperomia pellucida reduces inflammation in ARPE-19 eye cells exposed to high glucose and advanced glycation end products (AGEs) by exploring specific signaling pathways (NF-κB and PPAR-γ).
- Both the methanolic extract and ethyl acetate fraction of P. pellucida showed no toxicity to the cells and provided protection against cellular stress caused by high glucose levels and AGEs.
- Key phytochemicals in P. pellucida demonstrated strong binding to inflammatory proteins, suggesting their potential role in inhibiting the inflammatory response in these retinal cells.
Article Synopsis
- The abdomen is commonly affected in trauma cases, with blunt trauma being more dangerous than penetrating trauma, often leading to serious outcomes.
- Diagnostic challenges in blunt abdominal trauma can result in delayed treatment, increasing the risk of morbidity and mortality, especially for hollow viscus and mesenteric injuries.
- A case study highlights a 48-year-old male with a mid-ileal mesenteric tear and perforation who was treated successfully after a 96-hour delay post-injury through laparotomy and primary anastomosis.
Article Synopsis
- The paper discusses the creation of melamine-based metal-organic frameworks (MOFs) using cheap melamine as an organic linker and cobalt, nickel, and iron as central metal ions for supercapacitor applications.
- It presents techniques to optimize the molecular structures of these MOFs, which were characterized through various methods like X-ray diffraction, electron microscopy, and thermal analysis to confirm their stability and performance.
- The electrochemical tests reveal that the specific capacitance values for Co-Me, Ni-Me, and Fe-Me in a potassium hydroxide electrolyte are significantly high, with Co-Me achieving 1267.36 F/g, indicating their efficiency in energy storage applications.
Small molecule therapeutics represent the majority of the FDA-approved drugs. Yet, many attractive targets are poorly tractable by small molecules, generating a need for new therapeutic modalities. Due to their biocompatibility profile and structural versatility, peptide-based therapeutics are a possible solution.
View Article and Find Full Text PDFAssessment of lung involvement using HRCT among vaccinated and non-vaccinated elderly COVID-19 patients admitted in a designated hospital, Tamil Nadu - A retrospective study.
J Family Med Prim Care
September 2023
Introduction: The COVID-19 pandemic is considered one of the most devastating situations globally, the worst affected were the senior citizens. A number of initiatives were carried out to control the COVID-19 pandemic; one such important measure is the development of COVID-19 vaccines to prevent the disease. But the continuous emergence of new SARS-COV2 variants (antigenic drift) and its demographic variation in virulence makes the vaccine's efficacy questionable.
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