Cigarette smoke exposure can lead to neurocognitive dysfunction, and this study investigates the effects of ambrisentan, a selective endothelin-A receptor antagonist, on cognitive impairment caused by cigarette smoke in zebrafish.
The study involved exposing zebrafish to cigarette smoke for five days, followed by treatment with ambrisentan and comparing its effects with donepezil, a known cognitive enhancer.
Results indicated that ambrisentan improved cognitive functions and biochemical changes in the zebrafish, suggesting it may be a viable treatment for cigarette smoke-induced cognitive impairment due to its anti-inflammatory and neuroprotective properties.
Background And Aims: Cesarean sections are performed mostly under spinal anesthesia. Shivering is one of the distressing complications. The aim of the study was to compare the efficacy of intravenous (i.