Publications by authors named "B Arjmand"
Article Synopsis
- Platinum-based chemotherapies are crucial for treating various cancers but can lead to significant kidney damage, complicating treatment.
- Doctors may adjust chemo plans and prescribe medications to protect the kidneys, while new imaging and biomarkers help detect kidney issues early.
- Collaboration among oncologists, nephrologists, and pharmacists is essential, but more research is needed for tailored treatments and to minimize kidney injury from these drugs.
Article Synopsis
- - Glioblastoma, the most common and aggressive brain cancer, has a very poor survival prognosis, making it critical for detailed molecular studies to improve understanding and treatment.
- - This study uses bioinformatics tools to analyze gene expression in normal brain cells compared to glioblastoma cells, identifying a set of differentially expressed genes (DEGs) including TP53, EGFR, FN1, JUN, and CDC42 that could serve as biomarkers.
- - The identified genes are implicated in the stability of protein-protein interaction networks and may be promising targets for drug development in treating glioblastoma, pending further validation.
Introduction: Metformin is an essential medicine that is most widely prescribed frontline for the treatment of Type 2 diabetes (T2D). Metformin upgraded glycemic control in T2D patients without hypoglycemic effects in patients. This assessment aims to understand molecular mechanism mechanisms in non-responder patients to metformin.
View Article and Find Full Text PDFThe retina is a light-sensitive tissue, and intensive light exposure leads to light-induced retinal damage. It is pointed out that photoreceptor damage is responsible for the decrease in retina function. The aim of this study was to detect the main genes and biological terms which are involved in retinal response to intensive light exposure.
View Article and Find Full Text PDFStage analysis of pancreatic ductal adenocarcinoma via network analysis.
Gastroenterol Hepatol Bed Bench
January 2024
Aim: This study aimed to introduce a biomarker panel to detect pancreatic ductal adenocarcinoma (PDAC) in the early stage, and also differentiate of stages from each other.
Background: PDAC is a lethal cancer with poor prognosis and overall survival.
Methods: Gene expression profiles of PDAC patients were extracted from the Gene Expression Omnibus (GEO) database.